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Take one Gralise tablet each night after dinner. To ensure proper absorption, take the tablets with a full glass of water as instructed. You should take the pills by mouth. Avoid breaking it by chewing on it or crushing it.

Horizant tablets are best swallowed with food. The tablets should be taken with a full glass of water as advised. Do not put it in your mouth, smash, or abuse it.

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Gabapentin is a medication that helps with nerve pain and muscle spasms. Gabapentin works by binding to the GABA receptor in the brain that normally assists in producing calming neurotransmitters. This medication is also used for fibromyalgia, a chronic pain disorder that causes deep and persistent muscle pain.

Gabapentin interacts negatively with other antidepressants, including selective serotonin re uptake inhibitors (SSRIs) and mono amine oxidase inhibitors